Karma Runes is the latest Content related to the Rune System.
Karma Runes boosting your Character aswell as Essence Runes by being always active and dont need any Trigger System like Blended Runes.
Karma Runes can only be obtained by "Karma Rune Exchange Ticket" which can be gathered by the System "Dungeon of the Day". Find out more about the "Karma Rune Exchange" Tickets here: Karma Rune Exchange Ticket
Source
Karma Runes can be bought at "Rune Agent Flasha" in Bloody Ice Town
Currently there are only a few Runes available. You can find a complete List of supported Runes and their Requirements for Purchase check here: Rune List
